Title Details: | |
Thrombosis and anticoagulant therapy |
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Authors: |
Politi, Marianna |
Reviewer: |
Konstantopoulos, Konstantinos |
Subject: | MEDICINE AND HEALTH SCIENCES, LIFE SCIENCES, BIOLOGICAL SCIENCES > HEALTH SCIENCES > MEDICINE > CLINICAL MEDICINE MEDICINE AND HEALTH SCIENCES, LIFE SCIENCES, BIOLOGICAL SCIENCES > HEALTH SCIENCES MEDICINE AND HEALTH SCIENCES, LIFE SCIENCES, BIOLOGICAL SCIENCES > HEALTH SCIENCES > MEDICINE > PATHOLOGY MEDICINE AND HEALTH SCIENCES, LIFE SCIENCES, BIOLOGICAL SCIENCES > HEALTH SCIENCES > MEDICINE > PUBLIC HEALTH > PREVENTIVE MEDICINE |
Description: | |
Abstract: |
Thrombosis is the formation of a blood clot ( fibrin and / or platelet clot ) which obstructs blood flow in a vein or an artery. Virchow's triad explains the pathophysiology of venous thrombosis: impaired blood flow, endothelial vascular damage and disorders of the coagulation cascade .Thrombophilia (inherited and acquired), increases the predisposition to thrombosis. Main causes of inherited thrombophilia are : factor VLeiden, prothrombin mutation G20210A and deficiencies of the natural coagulation inhibitors (protein C, S and antithrombin). Thrombosis treatment includes unfractioned heparin, LMWH, , vitamin K antagonists (coumarins), direct inhibitors of factor Xa and direct inhibitors of thrombin and the new oral anticoagulants ( oral inhibitors of factor Xa and thrombin)
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Linguistic Editors: |
Klada, Nektaria |
Graphic Editors: |
Papakosmas, Ioannis |
Type: |
Chapter |
Creation Date: | 2015 |
Item Details: | |
License: |
http://creativecommons.org/licenses/by-nc-sa/3.0/gr |
Handle | http://hdl.handle.net/11419/3089 |
Bibliographic Reference: | Politi, M. (2015). Thrombosis and anticoagulant therapy [Chapter]. In Loukopoulos, D., & Politi, M. 2015. Hematology lessons [Undergraduate textbook]. Kallipos, Open Academic Editions. https://hdl.handle.net/11419/3089 |
Language: |
Greek |
Is Part of: |
Hematology lessons |
Number of pages |
7 |
Publication Origin: |
Kallipos, Open Academic Editions |